[Magdalen] Pharmaceutical question...

[Cantor03 at aol.com]

In a message dated 4/9/2015 9:11:48 P.M. Eastern Daylight Time,  
gracecan at gmail.com writes:

impression that that was not the case with steroid injections,  which is
why they are preferred for longtime anti-inflammatory  relief.>>>
 
I think this is incorrect.  In the end, the same side effects can  be
caused by injectable as by oral steroids.  Both orally and by  injection
these are dose dependent.
 
Intralesional, intra-articular, etc., injections are usually smaller  total
doses, and not repeated frequently, but even these do end up in
circulation.
 
For that matter also topical (creams and ointments) are absorbed
right through the skin, and the amount varies with concentration of
the salve, amount of skin covered, age of the person (kids have  thinner
skin), amount of existing trauma where salves are applied, and  whether
or not there is natural (skin to skin) or artificial (plastic wrap)  
occlusion.
 
 
David Strang.